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House and the team take on the case of a high-profile fitness trainer who collapses while shooting an infomercial. Meanwhile, Thirteen begins her participation in a clinical drug trial for Huntington's disease led by Foreman, Kutner sets up and runs an online medical advice clinic under House's name and Cuddy moves into House's office while hers is being repaired, much to the dismay of her new officemate.
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